Dynamic Testing for PPID in Donkeys

Spanish and US researchers evaluated dynamic testing for PPID in donkeys.
Author:
Publish date:
fat donkey behind fence

The TRH stimulation test is recommended as a dynamic test for the diagnosis of PPID in donkeys.

This prospective study by S. Mejia‐Pereira and colleagues in Spain and the USA aimed to evaluate dynamic testing for PPID in donkeys. This is an open-access study.

Six donkeys with clinical signs consistent with PPID and a basal adrenocorticotropic hormone (ACTH) concentration >50 pg/mL were included in the study. A dexamethasone suppression test (DST), thyrotropin‐releasing hormone (TRH) stimulation test and combined DST-TRH challenge were performed in all animals during the summer months with a 1‐week washout period between tests.

The TRH stimulation test identified all six donkeys as having PPID, whereas the DST and the DST-TRH identified 3/6 and 4/6 donkeys, respectively. Agreement between the DST and the DST-TRH tests was poor.

Bottom line: The TRH stimulation test is recommended as a dynamic test for the diagnosis of PPID in donkeys.

The authors of this study were Mejia‐Pereira, S.; Perez‐Ecija, A.; Buchanan, B.R.; Toribio, R.E.; and Mendoza, F.J.

This open access article can be accessed  on the Wiley online library

AAEP-MediaPartner_1968x1100
AVMA-PLIT-logo_resized
BEVA-logo_3757x2100
WEVA-Logo-Dark-Background_1789x1000
NZEVA-logo_1100x1968

ISELP-logo_1100x1968

AAEVT-logo_2050x3667