Microbes have the ability to resist antisepsis through strategies like biofilms. Therefore, effective bactericidal products that have disinfectant efficacy at low concentrations, are safe in the environment, and have low corrosive properties are necessary in medical spaces. Researchers in Russia recently evaluated a new disinfectant called Aseptobrom, which contains the active ingredients didecyldimethylammonium bromide and isopropyl and polyoxyethylated alcohol, for veterinary disinfection.
The researchers diluted the concentrated solution with distilled water. They tested various concentrations on wood, concrete, ceramic tile, and stainless steel to evaluate efficacy against Escherichia coli, Staphylococcus aureus, and Mycobacterium. Effectiveness in the testing equated to 100% death of test microorganisms.
Bactericidal activity was more potent against S. aureus than E. coli. On smooth surfaces, Aseptobrom at 0.1% concentration over an hour was effective. On rough, moisture-absorbing surfaces (wood, concrete), efficacy was achieved at 1% solution for three hours. For S. aureus, smooth surface disinfection occurred at 0.1% solution for one hour; for rough, moisture-absorbing surfaces, it required 0.4% solution for three hours. (The authors noted that other disease-causing organisms will likely respond to similar protocols.) For Mycobacterium strains, double treatment of rough surfaces required 6% concentration for three hours applied again after an hour and retained for 24 hours. Higher concentrations (9%) for 24 hours might be effective against Mycobacterium species on wood or concrete when applied only once.
Corrosion testing on steel and aluminum revealed that Aseptobrom is more corrosive than 2% sodium hydroxide solution, even at one hour. In general, however, Aseptrobrom “does not have a high corrosive effect on metal surfaces.”
Reference
Shcherbakova GS, Popov NI, Shuteeva EN, et al. Antimicrobial properties of a new bactericide for veterinary disinfection. BIO Web of Conferences 2025, vol. 161, 00036; DOI: 10.1051/bioconf/202516100036.
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